Proven Data Quality Solutions

We provide customized data quality solutions with these proven methods

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Risk-Based Data Monitoring (RBDM)

Sophisticated, instrument-specific algorithms detect potential data inconsistencies in real-time so that they can be addressed immediately, and prevented from reoccurring in the future.

Expert clinician review determines if the detected discrepancies are problematic, and predefined intervention strategies are implemented based upon the level of risk determined.

Identified issues and interventions are tracked and communicated via customized reports, live meetings, and in accordance with predefined escalation paths.

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Retrospective Analysis

Proprietary data monitoring algorithms are used to identify the relative risk level associated with the data and demonstrate the impact of non-informative (inconsistent/improbable) data on statistical power.

Retrospective analysis results serve as the basis for sponsor decisions regarding future protocol design, to proactively address challenges in future studies (e.g., patient enrollment, sample size, outcome measures, site selection).

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Rater Training

Cronos’ unique approach to Rater Training is based on over a decade of data monitoring-related interactions with raters. It addresses the kinds of errors and behaviors raters actually engage in during the course of the trial. In addition, protocol-specific considerations and scale-specific scoring and administration guidelines are provided to ensure consistency.

Training can be delivered via Cronos’ online platform or live.

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Protocol Compliance Platform (CIRP)

Cronos’ Integrated Research Platform (CIRP) is an online management tool specifically designed to proactively eliminate clinical trial protocol violations through streamlining of communication, implementation of hard/soft validations, and ease of use.

CIRP has also been formulated to make the operationalization and project management of large complex global clinical trials less time-consuming by implementation of capabilities such as one-click language localization, automated time-zone conversion, and integrated technology communication across devices and supporting software (e.g., Office and Outlook). CIRP makes clinical trial execution seamless to the site, study team, and third party service providers.